BIOCHEMISTRY: BUILDING BLOCKS OF LIFE - 2017/8

Module code: BMS1030

Module provider

School of Biosciences and Medicine

Module Leader

TRINDER S Dr (Biosc & Med)

Number of Credits

15

ECTS Credits

7.5

Framework

FHEQ Level 4

JACs code

C700

Module cap (Maximum number of students)

N/A

Module Availability

Semester 2

Overall student workload

Independent Study Hours: 120

Lecture Hours: 32

Tutorial Hours: 3

Laboratory Hours: 3

Assessment pattern

Assessment type Unit of assessment Weighting
Practical based assessment PRACTICAL PROFORMA 40
Examination EXAM 60

Alternative Assessment

Data analysis Qualifying condition(s) A weighted aggregate mark of 40% is required to pass the module

Prerequisites / Co-requisites

BMS1050

Module overview

In this module students will be taken on a learning journey through protein structure and function, emphasising their importance in the biochemical processes which occur within living cells. Students will explore the contributions of lipid molecules and sugars to cellular ATP production, and will be introduced to the important role that the TCA cycle and electron transport systems have in production of ATP.  Students will undertake practical classes which highlight and develop the concepts taught within the module, and which will enhance their understanding of the key concepts.  

Module aims

Develop confidence and competence with practical and analytical skills in key biochemical methods.

Provide a breadth of understanding of the levels of protein structure, and how amino acids infuence the three dimensional folding of protein molecules.

Provide a breadth of undertsanding of enzyme kinetics and mechanism of reaction.

Provide a breadth of understanding of the structure and function of lipid molecules and their synthesis, in particular the role of lipids in the generation of cellular energy.

Provide a breadth of understanding of the use of glucose in glycolysis and the importance of this process in the generation of cellular energy.

Provide a breadth of understanding of the essential role of the TCA cycle in maximising the yield of cellular enery from biological fuels.

Provide breadth of understanding of the process of electron transport and its importance in synthesising ATP, in addition to a comparison between light independent photosynthesis and the mitochondrial electron transport chain.

Learning outcomes

Attributes Developed
001 Protein structure and function • Describe the primary structure of a protein, and explain how this influences the secondary, tertiary and quaternary structures. KC
002 Enzyme kinetics • Describe the concepts of Km and Vmax, and explain how these parameters can be derived from simple experimental data KCPT
003 Glycolysis • Discuss key regulatory points within glycolysis and explain the importance of glycolysis within cellular ATP generation KC
004 Lipids • Highlight the role of lipids as a source of acetyl-coA for cellular metabolism, and explain their role in long term energy generation. KC
005 TCA cycle • Discuss the central role of the TCA cycle within cellular metabolism and explain how it maximises the production of ATP from sources of cellular fuel. KC
006 Electron transport chain • Compare and contrast the generation of ATP from the mitochondrial and chloroplast electron transport chains KC

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content

Indicative content includes:


Proteins and enzymes
Carbohydrates and glycolysis
Lipids and oxidation
TCA cycle
Electron transport and ATP synthesis

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

Enhance and develop the students understanding of biological reactions as processes and as parts of a larger whole. 

The learning and teaching methods include:


Lectures
2 Practicals
Inborn errors of metabolism and energy expenditure workshops

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate a deep understanding of the fundamental principles around molecular biochemistry and cellular energy generation.

 

Thus, the summative assessment for this module consists of:


One synoptic practical report
One exam with multiple choice questions


Formative assessment

Formative assessment will be through online MCQ and within practical classes and formative workshops

Feedback

Feedback will be continuous and linked to formative assessments practical classes and workshops, in depth feedback will be provided on the practical report submission. 

Reading list

Reading list for BIOCHEMISTRY: BUILDING BLOCKS OF LIFE : http://aspire.surrey.ac.uk/modules/bms1030

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Microbiology (Medical) BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Food Science and Microbiology BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biotechnology BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Microbiology BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Nutrition and Food Science BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Nutrition and Dietetics BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Nutrition BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Sport and Exercise Science BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.