STRUCTURE AND FUNCTION 1: CELLS AND GENES IN CONTEXT - 2017/8

Module code: VMS1003

Module provider

School of Veterinary Medicine

Module Leader

NALESSO G Dr (Vet Med)

Number of Credits

15

ECTS Credits

7.5

Framework

FHEQ Level 4

JACs code

D100

Module cap (Maximum number of students)

N/A

Module Availability

Semester 1

Overall student workload

Independent Study Hours: 98

Lecture Hours: 34

Tutorial Hours: 6

Assessment pattern

Assessment type Unit of assessment Weighting
Practical based assessment PRACTICAL LABORATORY REPORT 30
Examination WRITTEN EXAMINATION - MCQ & SHORT ANSWER QUESTIONS 50
Coursework GROUP POSTER ASSIGNMENT 20

Alternative Assessment

Resits for practical reports will involve the preparation of a reflective writing report on an area related to the failed module. Resits for the poster assignment will involve a written report in related subject area to be determined by the module coordinator.

Prerequisites / Co-requisites

Module overview


Understanding the molecular aspects of living cells is of vital importance for many other aspects of the veterinary curriculum. This module will combine lecture-based learning with scientific laboratory practical sessions. Initial laboratory skills will be acquired and techniques carried out will be relevant across various disciplines especially physiology and histology and pathology. The basic concepts of physiology will be introduced such as homeostasis of systems. 


 

Module aims

Provide an understanding of cells and how they work

Provide an understanding of the genetic factors in animal breeding

Provide students with a basic knowledge of physiological principles

Develop an appreciation for physiological feedback, control and regulatory mechanisms 

Learning outcomes

Attributes Developed
1 Apply basic scientific knowledge of cell biology and genetics in the context of the animal bodyRCVS KU 1, RCVS KU 2 KPT
2 Combine topical scientific knowledge in genetics with clinical implications such as animal breeding for certain phenotype characteristics RCVS KU 1, RCVS KU 2 KPT
3 Apply physiological principles to understand homeostasis RCVS KU 1, KU 3 KPT
4 Gain basic scientific laboratory skills RCVS KU 2 PT

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Module content





Topics


Practical session




Pro/eukaryotic cell structure and biochemistry of lipids


Visualising the cell – light microscopy, electron-microscopy




Plasma membrane structure and transport




Mitochondria and energy biochemistry and carbohydrates




Electron transport chains and proton pumps




Intracellular vesicular transport




Cytoskeleton and molecular motors


Histological tissue staining – cells in context –




Cell communication - Receptors




Receptors and Signalling Pathways 1 (Cell communication – cellular events controlled by signalling pathways, local versus distant control, cell surface or intracellular receptors, cytokines and their structure




Receptors and Signalling Pathways 2: The most important receptor types and function: ligate-gated ion channels, G protein-coupled receptors (GPCRs), receptor tyrosine kinases (RTKs) and nuclear receptors


Cytology preparations using and seeing staining techniques




Receptors and Signalling Pathways 3: Endocrine receptors and function of hormones and their structure




Cell cycle




Cell death




Stem cells




Genes and Inheritance, Mendelian principles


DNA, RNA extraction




Genes and Breeding for specific traits




Mitosis, Meiosis




Nucleus - Chromosomes




Nucleosomes, Chromatin, Genes, DNA and their biochemistry




DNA replication


PCR and agarose gels




DNA Replication controls, recombination and repair




Transcriptional control / gene expression


 




Posttranscriptional modification, mRNA




Translation - mRNA




Biochemistry of Protein synthesis, structure and folding




Enzymes + Hormones




Cellular mechanisms of deviance: oncogenes and cancer, protein mis-folding and oxidative stress




Mutations, polymorphisms, genetic maps and SNPs, sequencing and phylogeny

 




Physiological concepts – homeostasis, buffering systems, Henderson Hasselbalch equation, osmotic pressures etc.

 


 




Methods of Teaching / Learning

The learning and teaching strategy is designed to:

Develop the practical laboratory skills needed for progression in the Structure and Function modules

Provide the students some insight into use of on line learning resources

The learning and teaching methods include:

Lectures = 34 hours

Practical session in the laboratory = 12 hours

2 x Case-based discussions/on line sessions – 3 hours = 6 hours

Total 60 hours contact time

 

 

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate:

An understanding of microscope use and cell structure and the role of the microscope in diagnosis in veterinary practice

Their understanding of cell structure and function as well as basic genetics

Development of literature searching, critical thinking, presenting and writing skills in the area of applied genetics

Thus, the summative assessment for this module consists of:

Practical Laboratory report – 30%

Written examination – MCQ & Short answer questions - 50% (2 hours)

Group poster assignment – 20 %

 

Formative assessment and feedback

Formative assessment during the practical sessions

Comment of their practical reports will inform their writing for their final presentations and reports for the genetics component.

Reading list

Reading list for STRUCTURE AND FUNCTION 1: CELLS AND GENES IN CONTEXT : http://aspire.surrey.ac.uk/modules/vms1003

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Veterinary Medicine and Science BVMSci (Hons) 1 Compulsory A weighted aggregate mark of 50% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2017/8 academic year.