BIOCHEMISTRY - A CONCEPTUAL OVERVIEW - 2018/9

Module code: BMS1041

Module Overview

In this module students will be taken on a learning journey through protein structure and function, emphasising their importance in the biochemical processes which occur within living cells. Students will explore the contributions of lipid molecules and sugars to cellular ATP production, and will be introduced to the important role that the TCA cycle and electron transport systems have in production of ATP.  Students will undertake practical classes which highlight and develop the concepts taught within the module, and which will enhance their understanding of the key concepts.  

Module provider

School of Biosciences and Medicine

Module Leader

BAILEY I Dr (Biosc & Med)

Number of Credits: 15

ECTS Credits: 7.5

Framework: FHEQ Level 4

JACs code: C700

Module cap (Maximum number of students): N/A

Module Availability

Semester 2

Prerequisites / Co-requisites

BMS1049

Module content

Indicative content includes:


Proteins and enzymes
Carbohydrates and glycolysis
Lipids and oxidation
TCA cycle
Electron transport and ATP synthesis

Assessment pattern

Assessment type Unit of assessment Weighting
Practical based assessment PRACTICAL PROFORMA 40
Examination EXAM 60

Alternative Assessment

Data analysis

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate a deep understanding of the fundamental principles around molecular biochemistry and cellular energy generation.

 

Thus, the summative assessment for this module consists of:


One synoptic practical report
One exam with multiple choice and short essay questions.


Formative assessment

Formative assessment will be through online MCQ and within practical classes and formative writing workshops

Feedback

Feedback will be continuous and linked to formative assessments practical classes and workshops, in depth feedback will be provided on the practical report submission. 

Module aims

  • Develop confidence and competence with practical and analytical skills in key biochemical methods.
  • Provide a breadth of understanding of the levels of protein structure, and how amino acids infuence the three dimensional folding of protein molecules.
  • Provide a breaths of undertsanding of enzyme kinetics and mechanism of reaction.
  • Provide a breadth of understanding of the structure and function of lipid moleciles and their synthesis, in particular the role of lipids in the generation of cellular energy.
  • Provide a breadth of understanding of the use of glucose in glycolysis and the importance of this process in the generation of cellular energy.
  • Provide a breadth of understanding of the essential role of the TCA cycle in maximising the yield of cellular enery from biological fuels.
  • Provide breadth of understanding of the process of electron transport and its importance in synthesising ATP, in addition to a comparison between light independent photosynthesis and the mitochondrial electron transport chain.

Learning outcomes

Attributes Developed
001 Protein structure and function • Describe the primary structure of a protein, and explain how this influences the secondary, tertiary and quaternary structures KC
002 Enzyme kinetics • Describe the concepts of Km and Vmax, and explain how these parameters can be derived from simple experimental data KCPT
003 Glycolysis • Discuss key regulatory points within glycolysis and explain the importance of glycolysis within cellular ATP generation. KC
004 Lipids • Highlight the role of lipids as a source of acetyl-coA for cellular metabolism, and explain their role in long term energy generation. KC
005 TCA cycle • Discuss the central role of the TCA cycle within cellular metabolism and explain how it maximises the production of ATP from sources of cellular fuel. KC
006 Electron transport chain • Compare and contrast the generation of ATP from the mitochondrial and chloroplast electron transport chains. KC

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Overall student workload

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

Enhance and develop the students understanding of biological reactions as processes and as parts of a larger whole.  To further support and enhance the students writing and communication skills.

The learning and teaching methods include:


Lectures
2 Practicals
Writing and peer review workshops

Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.

Reading list

Reading list for BIOCHEMISTRY - A CONCEPTUAL OVERVIEW : http://aspire.surrey.ac.uk/modules/bms1041

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Biomedical Science BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biochemistry BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biological Sciences BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Veterinary Biosciences BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Microbiology BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2018/9 academic year.