TOPICS IN ORGANIC CHEMISTRY - 2021/2
Module code: CHE3043
In light of the Covid-19 pandemic, and in a departure from previous academic years and previously published information, the University has had to change the delivery (and in some cases the content) of its programmes, together with certain University services and facilities for the academic year 2020/21.
These changes include the implementation of a hybrid teaching approach during 2020/21. Detailed information on all changes is available at: https://www.surrey.ac.uk/coronavirus/course-changes. This webpage sets out information relating to general University changes, and will also direct you to consider additional specific information relating to your chosen programme.
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This module in organic chemistry moves from the predominantly functional group approach of Introductory beyond the skeletal construction approach of Intermediate, to deal with modern and more conceptually challenging reaction. These are the reactions that are commonly used in contemporary organic chemistry.
CUNNINGHAM Ian (Chemistry)
Number of Credits: 15
ECTS Credits: 7.5
Framework: FHEQ Level 6
JACs code: F160
Module cap (Maximum number of students): N/A
Indicative content includes:
- Revision of organic reactions: Revision of mechanisms
- Retrosynthetic Analysis: Terms, definitions and basic concepts; Retrosynthetic Analysis: Aromatic compounds; Retrosynthetic Analysis: Alcohols and carbonyl compounds; Retrosynthetic Analysis: 1,2, 1,3, 1,4 and 1,5dicarbonyl compounds; a,b-unsaturated and 1,3dihydroxy compounds; Retrosynthetic Analysis: Carbocyclic and heterocyclic; compounds
- Modern reactions: Polar reactions in synthesis, Radical reactions in synthesis, Pericyclic reactions in synthesis, Asymmetric synthesis – an introduction
- Catalytic reactions in organic chemistry: Concept of catalysis. Mechanistic implications: creating a catalytic cycle; Reactions using metal catalysis; Palladium-catalysed cross-coupling reactions: Heck, Sonogashira, Stille and Suzuki reactions; PausonKhand reaction. Small organic molecules as catalysts; BaylisHillman; reaction; Olefin metathesis
- Multicomponent reactions: Solid-phase synthesis and combinatorial chemistry
Spectroscopy: Workshop 1: Introductory revision problems using 1D NMR (1H, 13C), MS, IR, UV. Use of the coupling constant, Karplus equation, coupling in aromatic systems and long range coupling; Workshop 2: Use of COSY, HSQC, DEPT, HMBC and NOESY spectra in structure determination with worked examples; Workshops 3 & 4: Structural determination of compounds using natural products and synthetic compounds (terpenoids; oxygen heterocyclics (chalcones, flavonoids); alkaloids) as examples
|Assessment type||Unit of assessment||Weighting|
|Examination||EXAM 1.5 HOURS||70|
|School-timetabled exam/test||IN CLASS TEST (Spectroscopy)||15|
Normally none, but a piece of (standard-style) CW might replace the ICT
The assessment strategy is designed to provide students with the opportunity to demonstrate:
- Examination and coursework: Assimilation of knowledge and its application to problems in modern organic chemistry [LOs 1-5, a]
- ICT on spectroscopy: Ability assign structure based on spectra [LOs 4, a]
Thus, the summative assessment for this module consists of:
- Coursework: Problem solving on aspects of the course (15%, 18 h over 8 weeks) [LOs assessed 1-3, 5, a]
- ICT on spectroscopy: (15%, 2 h ICT) [LOs 4, a]
- Examination: 1.5 hours, closed book [LOs assessed 1-5, a]
Formative assessment Formal formative assessment is in mainly in the spectroscopy workshops. Formal formative assessment is in the form of example problems posted to SurreyLearn for students to attempt and receive written or verbal feedback; also students can opt for informal informative formative assessment (submission of specimen exams, past papers, etc.) which will be marked and annotated.
Feedback: Occasionally following enquiries during/after lectures. Feedback is also provided optionally on the formative practice problems. CW is marked and returned with feedback in time for the revision period
- To provide students with the appropriate advanced material in organic chemistry to allow them to describe and methodically rationalize a representative range of standard reactions/syntheses
- To identify compounds by spectroscopy.
|001||Demonstrate a conceptual understanding of modern advanced organic reactions (including their scope), including abstract ones (combinatorial)||K|
|002||Explain chemo-, regio- and stereo-selectivity in given reactions||KC|
|003||Analyse a chemical structure in terms of the retrosynthetic approach to synthesis||KC|
|004||Solve problems of structure using a range of spectroscopic techniques, particularly NMR||KCP|
|005||Show critical evaluation of different approaches to specific problems in synthesis||C|
|006||Transferrable Skills developed and included in units of assessment (a. Reviewing, assessing, and critical thinking.||T|
C - Cognitive/analytical
K - Subject knowledge
T - Transferable skills
P - Professional/Practical skills
Overall student workload
Workshop Hours: 10
Independent Study Hours: 120
Lecture Hours: 22
Methods of Teaching / Learning
The learning and teaching strategy is designed to:
give the student a good high level knowledge base, but also but the analytical and problem-solving skills to solve unseen (but related), and to attempt some new concepts; all within the context of current practice in organic synthesis
The learning and teaching methods include:
Lectures (2 per week x 10 = 20 L)
Problem-solving CW based on the lectures (18 h over 8 weeks)
Spectroscopy workshop (Contact =4 x 2 h over 8 weeks, plus self-study time ca. 18 h, plus ICT/assessed w/shop 2 h)
Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.
Reading list for TOPICS IN ORGANIC CHEMISTRY : http://aspire.surrey.ac.uk/modules/che3043
Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2021/2 academic year.