Module code: BMS2035

Module Overview

This module will cover two broad topics, namely Metabolism in Health & Disease (Dr Alfred Thumser, Dr Ian Bailey) and Cell Signalling (Dr Ian Bailey)

Module provider

School of Biosciences and Medicine

Module Leader

THUMSER Alfred (Biosc & Med)

Number of Credits: 15

ECTS Credits: 7.5

Framework: FHEQ Level 5

JACs code: C700

Module cap (Maximum number of students): N/A

Overall student workload

Workshop Hours: 10

Independent Learning Hours: 110

Lecture Hours: 30

Module Availability

Semester 1

Prerequisites / Co-requisites

Pre-requisites: BMS1041 Biochemistry – A Conceptual Overview

Module content

Indicative content includes:

  • Diabetes

  • Metabolic control of glycolysis and gluconeogenesis

  • Pentose phosphate pathway

  • Fatty acid β-oxidation and synthesis

  • Cell signalling

  • G-protein coupled receptors

  • Enzyme linked receptors

  • Ion channel receptors

  • Nuclear receptors

  • Tyrosine kinase associated receptors, e.g. JAK/STAT pathway (self-study; to be advised)

  • Receptor serine-threonine, TGFbeta receptor (self-study; to be advised)

Assessment pattern

Assessment type Unit of assessment Weighting
School-timetabled exam/test ON-LINE MCQ TEST 1 20
School-timetabled exam/test ON-LINE MCQ TEST 2 20

Alternative Assessment

Not Applicable.

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate critical thinking and understanding of the taught topics

Thus, the assessments for this module consist of:

  • MCQ tests 1 & 2 (topics taught by Dr Alfred Thumser), 3 & 4 (topics taught by Dr Ian Bailey)

  • Final exam (one hour; two short essays; the exam will be in two sections (AET & IB) and candidates should attempt one question from each section; three essay questions per section ; linked to all Learning Outcomes)

Formative assessment and feedback:

  • Generic in-class post-MCQ feedback

  • Peer-to-peer feedback in small-group essay workshops

  • Feedback on final exam (on scripts and one-to-one, as requested, with generic on-line feedback)

Module aims

  • Critically assess aspects of glucose and lipid metabolism
  • Discuss metabolic diseases in conjunction with metabolic pathways
  • Explain the concept of intracellular signalling pathways and its importance in cell function
  • Demonstrate the importance of protein phosphorylation in metabolic regulation.
  • Provide understanding on the surface and intracellular receptors and their major activated intracellular signalling pathways in health and disease
  • Discuss the importance of cellular signalling pathways in regulating gene transcription in health and disease

Learning outcomes

Attributes Developed
1 Define and describe glucose homeostasis ad control of glucose metabolism KC
2 Define and describe glucose metabolism in disease e.g. diabetes KC
3 Define and describe fatty acid metabolism, i.e. b-oxidation and synthesis KC
4 Define and describe the major plasma membrane and nuclear receptors KC
5 Descibe the intracellular signalling pathways activated by major plasma membrane and nuclear receptors and their role in controlling gene transcription in health and disease KC

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Methods of Teaching / Learning

The learning and teaching methods include:

  • Lectures

  • Tutorials

  • “Think-pair-share” [formative]

  • Small-group essay workshops [formative]


Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.

Reading list
Upon accessing the reading list, please search for the module using the module code: BMS2035

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Biochemistry BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Microbiology BSc (Hons) 1 Optional A weighted aggregate mark of 40% is required to pass the module
Biomedical Science BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biochemistry MSci (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Veterinary Biosciences BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biological Sciences BSc (Hons) 1 Compulsory A weighted aggregate mark of 40% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2019/0 academic year.