Module code: VMS2005

Module Overview

This module introduces the student to clinical pathology of body systems and to the pathology of the haematopoietic and lymphoid systems. The student will familiarise with the clinical pathology tests used to evaluate animal health; these will include haematology, biochemistry related to the function of different body systems and cytology of organs, fluids and neoplasia . The response of the haematopoietic and lymphoid systems to invasion by viruses, bacteria, parasites and fungal agents will be discussed. All diseases will be presented in context of One Health and underpinned with clinical case examples.

Module provider

School of Veterinary Medicine

Module Leader


Number of Credits: 15

ECTS Credits: 7.5

Framework: FHEQ Level 5

JACs code: D323

Module cap (Maximum number of students): N/A

Overall student workload

Independent Learning Hours: 97

Lecture Hours: 35

Tutorial Hours: 6

Practical/Performance Hours: 12

Module Availability

Semester 2

Prerequisites / Co-requisites

Successful completion of all First BVMSci year units

Module content

Terminology and appropriate units to use for a range of basic laboratory tests and laboratory test abnormalities. Factors affecting the calculations and use of reference intervals.

Uses and applications of laboratory tests in the evaluation of animal health and in the diagnosis, prognosis, and monitoring of disease in different animal species

Morphology, functions and main disorders of erythrocytes, leukocytes, and platelets; and the appropriate procedures to evaluate these cells in a blood smear.

Basis of the more important coagulation tests, and expected changes in test results in the common coagulopathies.

Main animal blood group systems and tests that should be carried out before a transfusion is performed

Basic criteria for the selection and interpretation of the results of biochemical tests for the clinical investigation in abnormalities of: glucose, lipid, ketone body and protein metabolism

  • liver, exocrine pancreas and gastrointestinal tract, urinary system, muscle, endocrine organs, electrolyte, acid/base, and mineral values.

Exfoliative cytology of masses, organs and body fluids other than blood

Plan and equip an in-practice laboratory, including basic instruments, stains, reagents and other supplies; and carry out a range of simple haematological, biochemical and cytological tests

Interpret laboratory test results using appropriate reference intervals and with consideration of available clinical information


Pathology of the haematopoietic system – congenital, infectious, inflammatory, immune-mediated, toxic, congenital disorders, degenerative conditions

Neoplasia of the haemopoietic system, histopathology and cytology of lymphomas

Pathology and pathogenesis of infectious pathogens causing haemorrhagic (DIC) haemolytic diseases and septicaemia(Anthrax)

Blood protozoal infections I – Trypanosoma, Plasmodidae, Leishmania, Babesia, Theileria



Rickettsiales and Coxiella burnetii – bacteria targeting blood cells

Example of viral pathogens causing haemorrhagic diseases: Pathogenesis of  Flaviviridae

Orbiviruses, Asfarviridae




Haematology- evaluation of blood smears, haemograms, leukograms and proteins (3 hours)

Cytology of neoplasia, organs and fluids 3 hours



Biochemistry tests- 2 hours

Histopathology of lymphoid organs with cytology correlation- 2 hours

Lab equipment- 2 hours

PBL cases and case scenarios – 6 hours


Assessment pattern

Assessment type Unit of assessment Weighting
Practical based assessment PBL ASSESSMENT 10
Practical based assessment PRACTICAL REPORTS 10
Practical based assessment STEEPLECHASE 30

Alternative Assessment

PBL alternative assessment is an oral examination Practical report alternative assessment is the preparation of a reflective writing report on an area related this module

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate

  • Practical skills in examining, recognising, describing and interpreting gross and microscopic specimens and laboratory result abnormalities

  • Record writing ability and understanding and use of terminology

  • Encourage teamwork and participation in group learning both in the practical sessions and the PBL cases.

  • Content knowledge of general pathology and infectious and non-infectious disease mechanisms

Thus, the summative assessment for this module consists of:

  • Formative assessments: Instructor and peer assessments 0%

  • PBL assessment – 10%

  • Practical reports – 10%

  • Steeplechase - 30%

  • Written examination – 50%

Formative assessment and feedback

Formative assessments: Instructor and peer assessments 0%


Module aims

  • Provide a detailed understanding of clinical pathology and disease pathogenesis
  • Introduce the terminology of systemic haematopoietic and lymphoid pathology based on aetiopathogenesis, and gross and microscopic appearance of non-infectious and infectious lesions.
  • Increase the students ability to recognise, describe and interpret the abnormal and write a meaningful report using the appropriate terminology and methods to record findings

Learning outcomes

Attributes Developed
1 Describe the basic mechanisms of infectious and non–infectious diseases and apply acquired foundation knowledge relevant to the haematopoietic and lymphoid systems RCVS KU 1, KU 3, KU 5 KP
2 Understand what are the causes, development and consequences of infectious and non-infectious disease of the haematopoietic and lymphoid systems by using the principles of disease: injury, adaptation, inflammation and repair. RCVS KU 1, KU 5 KPT
3 Understand what are the causes, development and consequences of infectious and non-infectious disease of the haematopoietic and nervous systems by using the principles of disease: injury, adaptation, inflammation and repair. RCVS KU 1, KU 5  KPT
4 Examine gross and microscopic pathological specimens, to identify common pathological findings affecting the haematopoietic  and lymphoid systems and be able to describe the lesions and interpret them using appropriate terminology and methods for collecting data  - RCVS 35 KCPT
5 Appreciate the commonality of the infectious disease process across species including concepts of One Health, One Medicine - RCVS KU 1, KU 5  KCPT
6 Appreciate the clinical pathological methods and tests used to distinguish disease of the systems of the body - RCVS 21 RCVS 22, RCVS KU 5 KPT
7 Understand the pathogenesis of clinico-pathological changes in response to disease

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

  • Provide infectious and non-infectious disease pathology in the context of One health, One medicine

  • Allow students to develop skills in examining gross and microscopic pathological specimens, describing and interpreting them

  • Provide students with the skills to record pathological findings using appropriate terminology

  • Allow students to develop laboratory abilities and skills in interpreting abnormal laboratory results

The learning and teaching methods include:

Lectures, flipped classroom, small group sessions, PBL cases, practical classes using microscopy and anatomic pathologic specimens and images. 


Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.

Reading list
Upon accessing the reading list, please search for the module using the module code: VMS2005

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Veterinary Medicine and Science BVMSci (Hons) 2 Compulsory A weighted aggregate mark of 50% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2019/0 academic year.