ANALYTICAL AND CLINICAL BIOCHEMISTRY - 2020/1

Module Overview

The Module will cover a range of topics that will address analytical techniques in research and clinical laboratories, as well as addressing the analysis of data and aspects of quality control.

Module provider

School of Biosciences and Medicine

Module Leader

THUMSER Alfred (Biosc & Med)

Number of Credits: 15

ECTS Credits: 7.5

Framework: FHEQ Level 5

Module cap (Maximum number of students): N/A

Module Availability

Semester 2

Prerequisites / Co-requisites

Pre-requisites: BMS1041 Biochemistry: A Conceptual Overview and either BMS1049  Biochemistry: The Molecules of Life or BMS1050: Biochemistry: The  Many Molecules of Life and BMS2035 Biochemistry - Enzymes and Metabolism In taking this module, you cannot in the same year take BMS2053 or BMS2070.

Module content

Indicative content includes:

Lectures:

• Tools of Analytical Biochemistry


• Analytical Standards and Sample Preparation


• Spectroscopy: UV-Vis, fluorescence, luminescence, Infra-red


• Chromatography (TLC, HPLC, GC, size exclusion, ion exchange, affinity)


• SDS-PAGE, isoelectric focussing & western blotting


• Factors affecting interpretation of clinical laboratory tests


• Liver function tests (LFTs) and clinical cases


• Lipoproteins


• Lipids - clinical overview


• Plasma proteins


• Neonatal screening


• Inherited metabolic diseases


• Therapeutic drug monitoring


• Point of Care Testing (POCT)


• Evaluating Analytical Data (including overview of statistics: Regression, t-test, ANOVA)


• Mass spectrometry

• Urinalysis


• Statistics (in silico)

Assessment pattern

Alternative Assessment

Practical reports, with data provided for practical write up 1 and 2

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate:

• The practical reports will assess Learning outcomes 1-4


• The final exam will assess learning outcomes 1-4

• Practical reports (2´15% weighting); deadline 1 week after practical


• Final exam (70% weighting), which is MCQ-type questions (1.5 hrs; 90 questions)

• Feedback on practical reports


• Pre-exam tutorial


• MCQ questions on SurreyLearn


• Use of “think-pair-share” and “Elevator” exercise during lectures

Module aims

• Provide an overview of analytical techniques used in research and clinical laboratories
• Link taught topics to laboratory practicals
• Use a blended learning approach to the teaching of Analytical Biochemistry by incorporating lectures, concept-directed tasks and tutorials
• Develop a critical awareness of analytical techniques and the analysis/interpretation of data

Learning outcomes

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

• Develop critical thinking and analysis skills, related to the module content;
• Encourage discussion and participation in learning activities, related to the module content;
• Encourage independent learning.

The learning and teaching methods include:

• Lectures (3 hrs X 10 weeks)
• Pre- & post-practical tutorials (1 hr X 4)
• Pre-exam Tutorials
• Practicals (2 hrs X 2 weeks)
• “Think - pair - share” class exercises
• “Elevator” class exercises
• SurreyLearn Discussion forum
• SurreyLearn on-line tests (MCQ)

independent learning 112 hours

Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.

Reading list

https://readinglists.surrey.ac.uk
Upon accessing the reading list, please search for the module using the module code: BMS2043

Programmes this module appears in

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2020/1 academic year.