ANALYTICAL AND CLINICAL BIOCHEMISTRY - 2020/1

Module code: BMS2043

Module Overview

The Module will cover a range of topics that will address analytical techniques in research and clinical laboratories, as well as addressing the analysis of data and aspects of quality control.

Module provider

School of Biosciences and Medicine

Module Leader

THUMSER Alfred (Biosc & Med)

Number of Credits: 15

ECTS Credits: 7.5

Framework: FHEQ Level 5

JACs code: C741

Module cap (Maximum number of students): N/A

Module Availability

Semester 2

Prerequisites / Co-requisites

Pre-requisites: BMS1041 Biochemistry: A Conceptual Overview and either BMS1049  Biochemistry: The Molecules of Life or BMS1050: Biochemistry: The  Many Molecules of Life and BMS2035 Biochemistry - Enzymes and Metabolism In taking this module, you cannot in the same year take BMS2053 or BMS2070.

Module content

Indicative content includes:

Lectures:


  • Tools of Analytical Biochemistry

  • Analytical Standards and Sample Preparation

  • Spectroscopy: UV-Vis, fluorescence, luminescence, Infra-red

  • Chromatography (TLC, HPLC, GC, size exclusion, ion exchange, affinity)

  • SDS-PAGE, isoelectric focussing & western blotting

  • Factors affecting interpretation of clinical laboratory tests

  • Liver function tests (LFTs) and clinical cases

  • Lipoproteins

  • Lipids - clinical overview

  • Plasma proteins

  • Neonatal screening

  • Inherited metabolic diseases

  • Therapeutic drug monitoring

  • Point of Care Testing (POCT)

  • Evaluating Analytical Data (including overview of statistics: Regression, t-test, ANOVA)

  • Mass spectrometry



Practicals:


  • Urinalysis

  • Statistics (in silico)


Assessment pattern

Assessment type Unit of assessment Weighting
Practical based assessment PRACTICAL WRITE-UP 1 15
Practical based assessment PRACTICAL WRITE-UP 2 15
Examination EXAMINATION - MCQ QUESTIONS - 90 MINUTES 70

Alternative Assessment

Practical reports, with data provided for practical write up 1 and 2

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate:


  • The practical reports will assess Learning outcomes 1-4

  • The final exam will assess learning outcomes 1-4



Thus, the summative assessment for this module consists of:


  • Practical reports (2´15% weighting); deadline 1 week after practical

  • Final exam (70% weighting), which is MCQ-type questions (1.5 hrs; 90 questions)



Formative assessment and feedback


  • Feedback on practical reports

  • Pre-exam tutorial

  • MCQ questions on SurreyLearn

  • Use of “think-pair-share” and “Elevator” exercise during lectures


Module aims

  • Provide an overview of analytical techniques used in research and clinical laboratories
  • Link taught topics to laboratory practicals
  • Use a blended learning approach to the teaching of Analytical Biochemistry by incorporating lectures, concept-directed tasks and tutorials
  • Develop a critical awareness of analytical techniques and the analysis/interpretation of data

Learning outcomes

Attributes Developed Ref
1 Recognise analytical techniques that are commonly used in research and clinical laboratories KCT
2 Apply knowledge to the interpretation of data and reporting of results KCPT
3 Apply knowledge to specific tasks and problems as an independent learner KCPT
4 Demonstrate practical skills and interpret experimental results within the context of taught material. KCPT

Attributes Developed

C - Cognitive/analytical

K - Subject knowledge

T - Transferable skills

P - Professional/Practical skills

Overall student workload

Workshop Hours: 4

Independent Study Hours: 112

Lecture Hours: 30

Laboratory Hours: 4

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

• Develop critical thinking and analysis skills, related to the module content;
• Encourage discussion and participation in learning activities, related to the module content;
• Encourage independent learning.

The learning and teaching methods include:

• Lectures (3 hrs X 10 weeks)
• Pre- & post-practical tutorials (1 hr X 4)
• Pre-exam Tutorials
• Practicals (2 hrs X 2 weeks)
• “Think - pair - share” class exercises
• “Elevator” class exercises
• SurreyLearn Discussion forum
• SurreyLearn on-line tests (MCQ)

independent learning 111 hours

Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.

Reading list

Reading list for ANALYTICAL AND CLINICAL BIOCHEMISTRY : http://aspire.surrey.ac.uk/modules/bms2043

Programmes this module appears in

Programme Semester Classification Qualifying conditions
Microbiology BSc (Hons) 2 Optional A weighted aggregate mark of 40% is required to pass the module
Biomedical Science BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biological Sciences BSc (Hons) 2 Optional A weighted aggregate mark of 40% is required to pass the module
Biochemistry BSc (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module
Biochemistry MSci (Hons) 2 Compulsory A weighted aggregate mark of 40% is required to pass the module

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2020/1 academic year.