FOUNDATIONS OF DISEASE FIVE - PATHOLOGY OF THE HAEMOPOIETIC AND LYMPHOID SYSTEMS AND CLINICAL PATHOLOGY OF BODY SYSTEMS - 2021/2

Module Overview

This module introduces the student to clinical pathology of body systems and to the pathology of the haematopoietic and lymphoid systems. The student will familiarise with the clinical pathology tests used to evaluate animal health; these will include haematology, biochemistry related to the function of different body systems and cytology of organs, fluids and neoplasia . The response of the haematopoietic and lymphoid systems to invasion by viruses, bacteria, parasites and fungal agents will be discussed. All diseases will be presented in context of One Health and underpinned with clinical case examples.

Module provider

School of Veterinary Medicine

Module Leader

VAN VLIET Arnoud (Vet Med)

Number of Credits: 15

ECTS Credits: 7.5

Framework: FHEQ Level 5

Module cap (Maximum number of students): N/A

Module Availability

Semester 1

Prerequisites / Co-requisites

Successful completion of all First BVMSci year units

Module content

Terminology and appropriate units to use for a range of basic laboratory tests and laboratory test abnormalities. Factors affecting the calculations and use of reference intervals.




Uses and applications of laboratory tests in the evaluation of animal health and in the diagnosis, prognosis, and monitoring of disease in different animal species




Morphology, functions and main disorders of erythrocytes, leukocytes, and platelets; and the appropriate procedures to evaluate these cells in a blood smear.




Basis of the more important coagulation tests, and expected changes in test results in the common coagulopathies.




Main animal blood group systems and tests that should be carried out before a transfusion is performed




Basic criteria for the selection and interpretation of the results of biochemical tests for the clinical investigation in abnormalities of: glucose, lipid, ketone body and protein metabolism

• liver, exocrine pancreas and gastrointestinal tract, urinary system, muscle, endocrine organs, electrolyte, acid/base, and mineral values.

Exfoliative cytology of masses, organs and body fluids other than blood




Plan and equip an in-practice laboratory, including basic instruments, stains, reagents and other supplies; and carry out a range of simple haematological, biochemical and cytological tests




Interpret laboratory test results using appropriate reference intervals and with consideration of available clinical information




 




Pathology of the haematopoietic system – congenital, infectious, inflammatory, immune-mediated, toxic, congenital disorders, degenerative conditions




Neoplasia of the haemopoietic system, histopathology and cytology of lymphomas




Pathology and pathogenesis of infectious pathogens causing haemorrhagic (DIC) haemolytic diseases and septicaemia(Anthrax)




Blood protozoal infections I – Trypanosoma, Plasmodidae, Leishmania, Babesia, Theileria




 




 




Rickettsiales and Coxiella burnetii – bacteria targeting blood cells




Example of viral pathogens causing haemorrhagic diseases: Pathogenesis of  Flaviviridae




Orbiviruses, Asfarviridae




 




Practicals




 

Haematology- evaluation of blood smears, haemograms, leukograms and proteins (3 hours)




Cytology of neoplasia, organs and fluids 3 hours




 




 




Biochemistry tests- 2 hours

Histopathology of lymphoid organs with cytology correlation- 2 hours

Lab equipment- 2 hours




PBL cases and case scenarios – 6 hours





 

Assessment pattern

Alternative Assessment

PBL alternative assessment is an oral examination Practical report alternative assessment is the preparation of a reflective writing report on an area related this module

Assessment Strategy

The assessment strategy is designed to provide students with the opportunity to demonstrate

• Practical skills in examining, recognising, describing and interpreting gross and microscopic specimens and laboratory result abnormalities


• Record writing ability and understanding and use of terminology


• Encourage teamwork and participation in group learning both in the practical sessions and the PBL cases.


• Content knowledge of general pathology and infectious and non-infectious disease mechanisms

Thus, the summative assessment for this module consists of:

• Formative assessments: Instructor and peer assessments 0%


• PBL assessment – 10%


• Practical reports – 10%


• Steeplechase - 30%


• Written examination – 50%

Formative assessment and feedback

Formative assessments: Instructor and peer assessments 0%

 

Module aims

• Provide a detailed understanding of clinical pathology and disease pathogenesis
• Introduce the terminology of systemic haematopoietic and lymphoid pathology based on aetiopathogenesis, and gross and microscopic appearance of non-infectious and infectious lesions.
• Increase the students ability to recognise, describe and interpret the abnormal and write a meaningful report using the appropriate terminology and methods to record findings

Learning outcomes

Methods of Teaching / Learning

The learning and teaching strategy is designed to:

• Provide infectious and non-infectious disease pathology in the context of One health, One medicine


• Allow students to develop skills in examining gross and microscopic pathological specimens, describing and interpreting them


• Provide students with the skills to record pathological findings using appropriate terminology


• Allow students to develop laboratory abilities and skills in interpreting abnormal laboratory results

The learning and teaching methods include:

Lectures, flipped classroom, small group sessions, PBL cases, practical classes using microscopy and anatomic pathologic specimens and images. 

 

Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.

Reading list

https://readinglists.surrey.ac.uk
Upon accessing the reading list, please search for the module using the module code: VMS2005

Programmes this module appears in

Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2021/2 academic year.