HUMAN GENETICS IN THE 21ST CENTURY - 2022/3
Module code: BMS3093
The purpose of this module is to give students a clear view of how and where genetics is used in the ‘real world’. This module will build on the basics of molecular biology and genetics taught in Levels 4 and 5, and will expect students to utilise this prior knowledge and content given in lectures and in the problem-based learning assessments.
School of Biosciences and Medicine
BAILEY Sarah (Biosc & Med)
Number of Credits: 15
ECTS Credits: 7.5
Framework: FHEQ Level 6
JACs code: C420
Module cap (Maximum number of students): N/A
Overall student workload
Workshop Hours: 8
Independent Learning Hours: 105
Seminar Hours: 20
Tutorial Hours: 6
Captured Content: 11
Prerequisites / Co-requisites
BMS1047. BMS2036 is recommended.
Indicative content includes:
Inheritance patterns and interpretation of pedigree trees.
Methods used to identify & distinguish between mutations and their application in human diseases.
Use of bioinformatics to compare & contrast gene sequences across multiple species or from multiple sources.
Inheritance of epigenetic control of gene expression.
Human genetic disease diagnostics (to include ethics and genetic counselling)
Diagnostic tools for identification of somatic cancer cell genetics.
- Human complex disease research and the effects of the environment and genes on these
|Assessment type||Unit of assessment||Weighting|
|Coursework||INDIVIDUAL PROBLEM BASED LEARNING||33|
|Coursework||EXTENDED MATCHING QUESTIONS||33|
|Oral exam or presentation||Oral Presentation||34|
The assessment strategy is designed to provide students with the opportunity to demonstrate a clear and deep understanding of the different aspects of genetics in the 21st century, and to show their independent learning skills acquired during the course.
Three summative assessment for this module consists of:
Two individual assignments and one piece of group work, some elements of the group work will be based on individual performance. These will all be based on a case study or problem based learning approach, covering three different aspects of the course, deadlines will be dispersed evenly across the semester (33.3% of mark each). This will test the students’ ability to communicate clearly and concisely, which is a very important skill for a scientist.
Use of small-group PBL sessions will provide opportunity for peer feedback. Students will be able to assess his/her progress/performance against the class, because the group assessment sessions will be interactive.
There will be a formal class debate on some aspect of the ethics of genetics – this will be compulsory, students will participate to gain marks on one of the summative assessments. There will be opportunity to gain immediate formative feedback as to their levels of knowledge and understanding on ethical principles.
- Enable the students to gain a clear and deep understanding of use of bioinformatics to identify genetic abnormalities and interrogate their effects.
- Enable the students to gain a clear and deep understanding of epigenetic signature inheritance & influence on phenotype.
- Enable the students to gain a clear and deep understanding of inheritance patterns and ability to predict heritability of a trait.
- Enable the students to gain a clear and deep understanding of human genetic disease diagnostics (including ethics & genetic counselling)
- Enable the students to gain a clear and deep understanding of human cancer somatic molecular genetic diagnostics
- Enable the students to gain a clear and deep understanding of human complex (genes/environment) disease research
|001||Interpret a genetic history and predict future inheritance of a disease based upon this.||KCT|
|002||Interrogate and manipulate human databases.||KCPT|
|003||Compare and contrast genetic and epigenetic mechanisms stating their influence upon human disease||KCT|
|004||Evaluate the ethical, practical, and molecular genetic merits surrounding human genetic disease and be able to communicate an opinion giving the reasoning behind this||KCT|
|005||Summarise the results obtained from a genetic study and identify the diagnostics that may be used to gain further genetic insight into a disease.||KCPT|
|006||Describe, with examples, the molecular basis of somatic cancer mutations.||KCT|
|007||Illustrate the role of genetics in current human complex disease research and propose alternative or additional research questions and/or methods.||KCT|
C - Cognitive/analytical
K - Subject knowledge
T - Transferable skills
P - Professional/Practical skills
Methods of Teaching / Learning
The learning and teaching strategy is designed to: enable students to be independent learners and thereby gain a deep understanding of genetics as it is actually used today.
The learning and teaching methods include:
Seminars covering the main bulk of the content.
Class tutorials, using the ‘flipped classroom’ approach; facilitated, small-group, PBL sessions.
Workshops to help you understand the assessment strategy and prepare your mindset.
Peer-assisted learning will be achieved through group work for most tutorials and workshops sessions.
Formal class debate workshop on an aspect of the ethics of genetics(compulsory attendance).
captured conent (roughly 30-45 minutes per week).
In total approximately 34 hours of contact time.
Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.
Upon accessing the reading list, please search for the module using the module code: BMS3093
Programmes this module appears in
|Biomedical Science BSc (Hons)||2||Optional||A weighted aggregate mark of 40% is required to pass the module|
|Biomedical Science MSci (Hons)||2||Optional||A weighted aggregate mark of 40% is required to pass the module|
|Biochemistry BSc (Hons)||2||Optional||A weighted aggregate mark of 40% is required to pass the module|
|Biochemistry MSci (Hons)||2||Optional||A weighted aggregate mark of 40% is required to pass the module|
|Biological Sciences BSc (Hons)||2||Optional||A weighted aggregate mark of 40% is required to pass the module|
Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2022/3 academic year.