METABOLIC NUTRITION - 2023/4
Module code: MHUM003
This module examines the critical role of energy balance in the control of body weight, with focus on physiological mechanisms of appetite regulation, energy intake and expenditure in relation to weight gain and obesity. It evaluates the links between excess body fat and cardiovascular disease (CVD) and explains how these links result from adverse changes in lipid metabolism and the molecular physiology of adipose tissue. These topics are then addressed within the context of how diet and lifestyle can promote and protect against the development of CVD, with critical appraisal of the evidence for the specific impacts of weight-loss and dietary macronutrients.
School of Biosciences and Medicine
GRIFFIN Bruce (Biosc & Med)
Number of Credits: 15
ECTS Credits: 7.5
Framework: FHEQ Level 7
JACs code: B400
Module cap (Maximum number of students): N/A
Overall student workload
Independent Learning Hours: 90
Seminar Hours: 8
Tutorial Hours: 10
Laboratory Hours: 3
Guided Learning: 9
Captured Content: 30
Prerequisites / Co-requisites
MHUM001 and MHUM002
Introduction to the module
Appetite and energy expenditure
Lipids and CVD
Adipose tissue physiology
Diet, Lipids and CVD
Data Handling Workshop
Obesity, weight loss and regain; Metabolic management of obesity
|Assessment type||Unit of assessment||Weighting|
|Examination Online||24-HOUR UNSEEN ONLINE TAKE-HOME EXAM||100|
Re-assessments will be a reworking of the original coursework using the same data (or if required, provided class data).
The¿assessment strategy¿is designed to provide students with the opportunity to demonstrate
Critical thinking and application of knowledge and skills gained to current international and national public health issues
Thus, the¿summative assessment¿for this module consists of:
1 piece of coursework (mid-module) on a data-based evaluation of a case study, with several short answer questions. This case study is similar in content and process to the case study in the Data Handling Workshop.
1 24 hour take home exam (end of module) consisting of data-based evaluation of a case study, with several short answer questions. This case study is similar in content and process to the case study in the Data Handling Workshop. 25 multiple choice questions and 2 questions from a choice of 4 questions, requiring essay-type answers
This will take place informally during teaching sessions and tutorials, and through
Written feedback within 3 weeks of submitting coursework, with the option of 1:1 face-to-face feedback within 4 weeks.
- To provide understanding of the variable strength of evidence produced from a hierarchy of experimental studies in nutrition
- To evaluate the role of energy expenditure and adaptive thermogenesis in the regulation of energy balance.
- To elucidate the mechanisms involved in the regulation of appetite and food intake and the dietary, behavioural and dietary factors which influence this
- To review the cardiovascular risk associated with the insulin resistant conditions of obesity and metabolic syndrome in relation to energy, adipose tissue and lipid metabolism
- To detail the metabolic regulation of lipid lipoprotein and fatty acid transport systems, and the impact of fatty liver disease to CVD. Review current evidence for the effects of dietary sterols, fatty acids, carbohydrates and alcohol on energy balance, lipoprotein and fatty acid metabolism in relation to cardio-metabolic disease
- To appreciate the complexities of weight loss and weight management in relation to the underlying metabolic and energetic consequence
- To understand the supporting evidence and rationale for current, government led (¿SACN¿) national and international guidelines for the intake of dietary fats, fibre, and free sugars. Also, to be able to contextualise these guidelines with respect to recommendations for disease risk management from other sources e.g. ¿NICE¿, social media
- To be capable of data-based evaluation of a human case history, involving the analysis and interpretation of data on dietary intake, energy balance, and CVD risk factors
|001||To be able to access and critically appraise the scientific literature; be cognisant of the principles governing the strength of scientific evidence (differentiate between associative and causal relationships by understanding the hierarchy of evidence (study designs and other determinant factors such as statistical power)).||KCT||D, E, S|
|002||To understand the physiological basis of the regulation of energy balance, and to use and translate this knowledge to critically appraise alternative models of e.g. carbohydrate-insulin model (CIM), and risk manage body weight and co-morbidity, respectively.||KCPT||E, R|
|003||To be familiar with the physiological and behavioural mechanisms controlling food and energy intake, and to be able to translate and apply this knowledge in the management of body weight and CVD risk||KCPT||E, R|
|004||To understand how abnormalities in the metabolism of blood lipids and adipose tissue increase CVD risk; to be able to apply this knowledge to analyse and interpret data for the differential diagnosis and management of CVD risk||KCPT||E, R|
|005||To understand the complexities of weight loss and weight regain and energy balance, and be able to apply this knowledge to manage the underlying metabolic and energetic consequences||KCT||E, R|
|006||To be well versed and capable of discussing the supporting evidence and rationale for current national and international guidelines on diet and lifestyle modification for reducing body weight, preventing obesity and CVD risk||KCPT||E, R, S|
|007||To be able to discuss dietary approaches for the prevention of obesity and management of CVD risk in the wider contexts of the sustainability of food biosystems, and impact on the global environment||KCPT||E, G, R, S|
C - Cognitive/analytical
K - Subject knowledge
T - Transferable skills
P - Professional/Practical skills
Methods of Teaching / Learning
The¿learning and teaching¿strategy is designed to:
Enable students to develop the knowledge, skills and critical thinking to be able to engage with nutrition-related issues concerning excess body weight, obesity and CVD in different contexts.
Engage students with different learning backgrounds and maximise their learning.
Students will learn how and where to access data, evaluate its relevance and apply their knowledge to current problems.
Students will begin to integrate what they have learnt in previous modules with their understanding of public health issues
The¿learning and teaching¿methods include:
Recorded lectures; face-to-face seminar/tutorials, which provide a summary of recorded lectures, and include active learning and question and answer discussion sessions (live-streamed and recorded); data handling workshop involving problem-solving evaluation of data-based case histories; and use of online resources (literature reviews and relevant supporting literature)
Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.
Upon accessing the reading list, please search for the module using the module code: MHUM003
How this module aligns to the 5 pillars of the curriculum
Digital Capabilities: Skills in using digital resources gained in previous modules (such as using SurreyLearn, literature searching, online learning and presentation tools) are built on during this module. While a selection of relevant literature (e.g. reviews, original research papers, articles in the social media) will be provided, students are also encouraged to familiarise themselves with searching and retrieving peer-reviewed literature from online databases (e.g. PubMed, Skopus).
Employability: The module provides students with the latest knowledge and understanding of the metabolic inter-relationships between energy balance, body weight and cardiovascular disease (CVD). It also equips students with the ability and skill to critically appraise the evidence for the role of diet and lifestyle factors in promoting and protecting against obesity and CVD. This knowledge and ability have multiple applications in the nutritional and dietetic management of human health and disease by health care professionals in clinical and public health settings in the UK and overseas.
Global and cultural capabilities: This module provides an overview of the epidemiological evidence in support of the relationship between dietary fats and CVD originates from cross-cultural studies performed in countries across the globe. The module also addresses the major differences in the metabolic inter-relationship between body fat composition and risk and endpoints of CVD between ethnic groups (White Caucasians, Afro-Caribbean, South Asian). Knowledge of these differences is of key importance to the management of CVD risk in different cultures.
Resourcefulness and resilience: This module develops behaviours and skills gained in MHUM001 and 002. The application and translation of knowledge to a ‘real-life’ scenario is provided by the evaluation of data-based case studies in the ‘Data Handling Workshop’ and coursework. These case studies require the students to think critically and independently in interpreting the health/disease risk status of the patient via the analysis of data on body composition, energy balance and blood biochemistry. The Students must then develop a risk management strategy which includes a package of appropriate therapeutic diet and lifestyle changes.
The Students are provided with the first case study for the Data Handling Workshop well in advance of the live feedback event. Students are expected to attempt a series of questions related to the health/disease risk status and risk management of the patient prior to the live feedback session, to maximise their engagement with, and understanding of the solutions. The second coursework case study is similar in content and process to the first. As in other modules, there is also the opportunity for the solutions of both case studies to be discussed on an individual basis with the students.
Sustainability: The sustainability of food biosystems includes provision of a diet that maintains health and prevents disease. In this respect, the module provides explicit details of all current UK (SACN) and global guidelines for the intake of dietary macronutrients for the maintenance of health and prevention of disease. It provides the historical background, and underlying evidence for these guidelines, and when appropriate, addresses controversial aspects that may be contrary to evidence-based recommendations. Broader aspects relevant to sustainability, including food production, processing, distribution, retail, and impact on global resources and the environment, are topics that are addressed throughout the module within the context of dietary macronutrients and metabolic health.
Programmes this module appears in
|Human Nutrition MSc||1||Compulsory||A weighted aggregate mark of 50% is required to pass the module|
Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2023/4 academic year.