INTRODUCTION TO BIOLOGY AND RADIATION BIOLOGY - 2024/5
Module code: PHYM048
This course starts with an overview of human biology, followed by a discussion of the nature of the interaction of ionising and non-ionising radiation with biological systems. The course emphasises the effects at the cellular level and the impact that this has on the individual and across the population. The behaviour and effects of ingested and inhaled radionuclides are also covered.
Mathematics & Physics
SCHETTINO Giuseppe (Maths & Phys)
Number of Credits: 15
ECTS Credits: 7.5
Framework: FHEQ Level 7
JACs code: C190
Module cap (Maximum number of students): N/A
Overall student workload
Independent Learning Hours: 117
Lecture Hours: 33
Prerequisites / Co-requisites
Indicative content includes:
Human Biology; the cell, cardiovascular system, respiratory system, digestive system, urinary system, endocrine system, skeletal system, nervous system and sensory systems.
Introduction to radiobiology: 5Rs of radiobiology, Biological Effective Dose
Primary events in the cell; deposition of energy from low and high LET radiations; molecular events; DNA damage and repair; cellular radiosensitivity; dose-rate and LET dependence; molecular genetics of radiation cancer, human variation in radiation sensitivity
Acute (non-stochastic) effects after whole and partial body irradiation; damage to red bone marrow, gut epithelium, gonads, optic lens and developing brain of the foetus, genetic effects of radiation; biological dosimetry
Radionuclides in man; the behaviour of radionuclides in the body including isotopes of tritium, caesium, strontium, iodine, radium and plutonium; ICRP biokinetic and dosimetric models; dose calculations; doses to the embryo and foetus
Concepts of epidemiological studies
Dosimetry, practical measurements and theoretical modelling, instrumentation, antennas
|Assessment type||Unit of assessment||Weighting|
|Examination||Examination 2 Hours||70|
The assessment strategy is designed to provide students with the opportunity to demonstrate their knowledge of the human anatomy and physiology and of the way radiation interacts with biological systems. It will also allow them to demonstrate their capability to research on a new topic and to independently build on knowledge acquired from lectures.
Thus, the summative assessment for this module consists of:
A 2 hour, closed book examination.
An essay (maximum 2000 words), to be submitted typically in Week 6, on a topic broadly related to the interaction of radiation with biological systems.
A revision class with tutorial questions will be done in Week 12.
Students receive written feedback on their coursework. A tutorial provides an opportunity for verbal feedback on any aspects of the course that are not understood.
- To provide an understanding of the human body and the effect on it of ionising radiation.
|001||Module Specific Skills: Perform a critical analysis of basic molecular cell and tissue structures and function and a description of the principles of anatomy||KC|
|002||Discipline Specific Skills: Describe the control systems of the human body and critically relate them to the way radiation affects them||KC|
|003||Apply their knowledge of radiation physics to understand basic radiobiology and genetics||KCP|
|004||Interpret case studies on radiation biology at the light of the mechanisms of interaction for ingested and inhaled radionuclides.||KPT|
|005||Personal and Key Skills: Appreciate science underpinning radiological protection standards||PT|
C - Cognitive/analytical
K - Subject knowledge
T - Transferable skills
P - Professional/Practical skills
Methods of Teaching / Learning
The learning and teaching strategy is designed to:
Provide students with the theoretical foundations necessary to understand the effect of different types of radiation on the human body.
Allow them to apply this knowledge to specific radiation protection problems.
The learning and teaching methods include:
36 hours of lectures, including both theoretical aspects and their application. Teaching is given via handouts, projection and white board presentations.
- One large group tutorial/question session.
Indicated Lecture Hours (which may also include seminars, tutorials, workshops and other contact time) are approximate and may include in-class tests where one or more of these are an assessment on the module. In-class tests are scheduled/organised separately to taught content and will be published on to student personal timetables, where they apply to taken modules, as soon as they are finalised by central administration. This will usually be after the initial publication of the teaching timetable for the relevant semester.
Upon accessing the reading list, please search for the module using the module code: PHYM048
Programmes this module appears in
|Medical Physics MSc||1||Compulsory||A weighted aggregate mark of 50% is required to pass the module|
|Nuclear Science and Applications MSc||1||Compulsory||A weighted aggregate mark of 50% is required to pass the module|
|Nuclear Science and Radiation Protection MSc||1||Compulsory||A weighted aggregate mark of 50% is required to pass the module|
|Physics MSc||1||Optional||A weighted aggregate mark of 50% is required to pass the module|
Please note that the information detailed within this record is accurate at the time of publishing and may be subject to change. This record contains information for the most up to date version of the programme / module for the 2024/5 academic year.